SCHEMBL108973

SCHEMBL108973

Cc1c(Br)cccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30340550 0.84 ALDH1A1 (0.46)
SCHEMBL21616726 0.84 ALDH1A1 (0.46)
SCHEMBL264714 0.84
Fluoride SCHEMBL28873958 0.82 ALDH1A1 (0.57)
SCHEMBL1005748 0.82
SCHEMBL11796842 0.82 ALDH1A1 (0.57)
SCHEMBL1316278 0.82 ALDH1A1 (0.57)
SCHEMBL2048644 0.80
SCHEMBL17186019 0.80
SCHEMBL1133275 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 867 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708112-A Synthesis method of natural product of Ribes isosteroid alkaloid 华东师范大学 2025-03-28 CN claimed
CN-110885343-A Mint-based dicarbo-phosphorus chiral tertiary phosphine derivative, and preparation method and application thereof 聊城大学 2020-03-17 CN claimed
US-20110184105-A1 Phenylene Oxo-Diester Plasticizers and Methods of Making EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-07-28 US claimed
CN-122059934-A PD-L1 protein degradation targeting chimeric and preparation method and application thereof 首都医科大学 2026-05-19 CN disclosed
US-12595251-B2 Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2026-04-07 US disclosed
US-12590062-B2 PD-1/PD-L1 inhibitors GILEAD SCIENCES, INC. (US) 2026-03-31 US disclosed
US-12583839-B2 PD-L1 antagonist compound ADLAI NORTYE BIOPHARMA CO., LTD. (CN) 2026-03-24 US disclosed
US-12534450-B2 Methods and compositions for targeting PD-L1 ALIGOS THERAPEUTICS, INC. (US) 2026-01-27 US disclosed
EP-4640052-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-29 EP disclosed
US-20250325660-A1 IMMUNOMODULATOR COMPOUNDS AND METHODS OF USE INCYTE CORP (US) 2025-10-23 US disclosed
EP-3483142-B1 AROMATIC ACETYLENE OR AROMATIC ETHYLENE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF BEIJING MAXINOVEL PHARMACEUTICALS CO LTD (CN) 2025-10-15 EP disclosed
WO-1986007086-A1 HARDLY INFLAMMABLE BIODEGRADABLE FUNCTIONAL LIQUIDS BASED ON BROMINATED ALKYL-BENZOLS HYDROCOR FORSCHUNGS- UND ANALYTIK GMBH (DE) 1986-12-04 WO disclosed
EP-0173331-A2 2,3-Dihydro-1H-indene derivatives, a process for preparing them and pharmaceutical compositions containing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-03-05 EP disclosed
EP-0045423-B1 PROCESS FOR THE ALPHA-HALOGENATION OF POSSIBLY SUBSTITUTED METHYL AROMATICS BAYER AG (DE) 1984-02-22 EP disclosed
EP-0045423-A1 Process for the alpha-halogenation of possibly substituted methyl aromatics BAYER AG (DE) 1982-02-10 EP disclosed
US-4223172-A DEHYDROGENATION HALOGENATIVE WITH PALLADIUM-PHOSPHINE COMPLEX CATALYST GULF RESEARCH & DEVELOPMENT COMPANY (US) 1980-09-16 US disclosed
US-4128556-A COMPLEXING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1978-12-05 US disclosed
US-4080337-A Multioxymacrocycle compounds containing pyridyl rings as part of the macrocycle THE UPJOHN COMPANY (US) 1978-03-21 US disclosed
US-4034007-A Process for the production of halogenated aromatic carboxylic acids TENNECO CHEMICALS, INC. (US) 1977-07-05 US disclosed
US-3965116-A COMPLEXING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1976-06-22 US disclosed