Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK10 | O94804 | 3/20 | 0.42 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911015 | 0.84 | STK10 (0.42) | STK10SLKCLK2GSK3AGSK3B | |
| SCHEMBL11089293 | 0.78 | HSP90AA1 (0.42) | STK10SLKGSK3AGSK3BALDH1A1 | |
| SCHEMBL10945305 | 0.75 | GSK3B (0.43) | GSK3BLMNAALDH1A1KMT2AMAPT | |
| SCHEMBL11094856 | 0.73 | KMT2A (0.40) | GSK3BALDH1A1HSP90AA1HSP90AB1KMT2A | |
| SCHEMBL10735327 | 0.72 | KMT2A (0.51) | LMNAALDH1A1HTTKMT2AMAPT | |
| SCHEMBL10946787 | 0.69 | KMT2A (0.43) | LMNAALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL10900284 | 0.66 | KMT2A (0.47) | LMNAALDH1A1HTTKMT2AMAPT | |
| SCHEMBL11091234 | 0.65 | ALDH1A1 (0.46) | LMNAALDH1A1HTTHSP90AA1HSP90AB1 | |
| SCHEMBL10945805 | 0.64 | RAD51 (0.40) | ALDH1A1MAPTKDM4EGAATSHR | |
| SCHEMBL10902046 | 0.64 | NPC1 (0.43) | LMNAALDH1A1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4632698-A | MITICIDES; HERBICIDES | UNION CARBIDE CORPORATION (US) | 1986-12-30 | — | — | US | disclosed |
| US-4551547-A | HERBICIDES | UNION CARBIDE CORPORATION (US) | 1985-11-05 | — | — | US | disclosed |