Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | COPS5 | Q92905 | 5/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898801 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CYP1A2KDM4ESMN1; SMN2PKM | |
| SCHEMBL2454062 | 0.91 | ALDH1A1 (0.37) | ALDH1A1CYP1A2KDM4ESMN1; SMN2PKM | |
| SCHEMBL10897593 | 0.85 | KDM4E (0.39) | ALDH1A1CYP1A2KDM4ESMN1; SMN2PKM | |
| SCHEMBL965927 | 0.85 | KDM4E (0.39) | ALDH1A1CYP1A2KDM4ESMN1; SMN2PKM | |
| SCHEMBL965928 | 0.85 | KDM4E (0.39) | ALDH1A1CYP1A2KDM4ESMN1; SMN2PKM | |
| SCHEMBL2537358 | 0.85 | ALDH1A1 (0.31) | ALDH1A1CYP1A2KDM4ESMN1; SMN2PKM | |
| SCHEMBL2537354 | 0.85 | ALDH1A1 (0.31) | ALDH1A1CYP1A2KDM4ESMN1; SMN2PKM | |
| SCHEMBL8819596 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CYP1A2KDM4ESMN1; SMN2PKM | |
| SCHEMBL8818146 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CYP1A2KDM4ESMN1; SMN2PKM | |
| SCHEMBL8819587 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CYP1A2KDM4ESMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4603129-A | Cephalosporin derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-29 | — | — | US | disclosed |
| US-4470983-A | BACTERICIDES, ANTIBIOTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |
| US-4293550-A | Cephalosporin derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |