Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3855356 | 0.85 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1POLBGAAMAPT | |
| SCHEMBL3345807 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1POLBGAAMAPT | |
| SCHEMBL16088846 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1POLBGAAMAPT | |
| SCHEMBL11194393 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1POLBGAAMAPT | |
| SCHEMBL1665202 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1POLBGAAMAPT | |
| SCHEMBL16090030 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1POLBGAAMAPT | |
| SCHEMBL16088845 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1POLBGAAMAPT | |
| SCHEMBL10386875 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1POLBGAAMAPT | |
| SCHEMBL11846412 | 0.77 | L3MBTL1 (0.54) | SMN1; SMN2ALDH1A1MAPTL3MBTL1ATM | |
| SCHEMBL16088843 | 0.77 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1L3MBTL1ATMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622332-A | Asymmetric diesters of Hantzsch dihydropyridines with hypotensive activity | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-11 | — | — | US | disclosed |