Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027931 | 0.82 | LDHA (0.50) | IDO1MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11511060 | 0.81 | NPC1 (0.47) | IDO1NPC1RAB9AALDH1A1NOTUM | |
| SCHEMBL10946287 | 0.78 | CNR2 (0.56) | IDO1MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10901074 | 0.77 | HSP90AA1 (0.45) | IDO1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11512598 | 0.77 | IDO1 (0.42) | IDO1MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL837812 | 0.75 | MEN1 (0.48) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL11679050 | 0.73 | IDO1 (0.50) | IDO1MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10899864 | 0.72 | CYP2A6 (0.56) | IDO1MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10840406 | 0.71 | IDO1 (0.52) | IDO1MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2030727 | 0.71 | FEN1 (0.66) | IDO1HSP90AA1HSP90AB1KMT2AALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613603-A | Compounds with a nitrogen-containing heterocyclic nucleus, and drugs in which they are present | SANOFI (FR) | 1986-09-23 | — | — | US | disclosed |
| US-4159375-A | 6- AND 7-Aryl-1,2,4-triazolo[4,3-b]-1,2,4-triazines | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | disclosed |