Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 15/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901585 | 0.87 | OPRD1 (0.57) | OPRD1OPRM1OPRK1OPRL1SLC6A4 | |
| SCHEMBL13529192 | 0.81 | OPRD1 (0.48) | OPRD1OPRM1OPRK1OPRL1HRH3 | |
| SCHEMBL10903271 | 0.78 | OPRD1 (0.57) | OPRD1OPRM1OPRK1SLC6A4SLC6A2 | |
| SCHEMBL11620858 | 0.77 | HRH3 (0.53) | OPRD1OPRM1OPRK1OPRL1SLC6A4 | |
| SCHEMBL13974437 | 0.76 | HRH3 (0.51) | OPRD1OPRM1OPRK1OPRL1SLC6A4 | |
| SCHEMBL2231026 | 0.75 | TP53 (0.56) | — | |
| SCHEMBL11590735 | 0.75 | TP53 (0.56) | — | |
| SCHEMBL25168550 | 0.74 | OPRD1 (0.66) | OPRD1OPRM1OPRK1 | |
| SCHEMBL25168549 | 0.74 | OPRD1 (0.66) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8012446 | 0.73 | TP53 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |