Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.71 |
| ▸ | NAAA | Q02083 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890203 | 1.00 | FAAH (0.71) | FAAHNAAAHTR2CDGKAEPHX1 | |
| SCHEMBL28111138 | 1.00 | FAAH (0.71) | FAAHNAAAHTR2CDGKAEPHX1 | |
| SCHEMBL28142323 | 1.00 | FAAH (0.71) | FAAHNAAAHTR2CDGKAEPHX1 | |
| SCHEMBL10604404 | 1.00 | FAAH (0.71) | FAAHNAAAHTR2CDGKAEPHX1 | |
| SCHEMBL10605569 | 1.00 | FAAH (0.71) | FAAHNAAAHTR2CDGKAEPHX1 | |
| SCHEMBL10602947 | 0.98 | FAAH (0.68) | FAAHNAAAHTR2CDGKAEPHX1 | |
| SCHEMBL1906190 | 0.92 | FAAH (0.71) | FAAHNAAAHTR2CDGKAEPHX1 | |
| SCHEMBL7914174 | 0.92 | FAAH (0.71) | FAAHNAAAHTR2CDGKAEPHX1 | |
| SCHEMBL1318219 | 0.92 | FAAH (0.71) | FAAHNAAAHTR2CDGKAEPHX1 | |
| SCHEMBL9245668 | 0.92 | FAAH (0.71) | FAAHNAAAHTR2CDGKAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622332-A | Asymmetric diesters of Hantzsch dihydropyridines with hypotensive activity | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-11 | — | — | US | disclosed |