SCHEMBL10901432

SCHEMBL10901432

CCOc1ccc2nc(C)cc(O)c2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.68
HSD17B10 Q99714 7/20 0.68
KDM4E B2RXH2 5/20 0.68
SMN1; SMN2 Q16637 4/20 0.68
HPGD P15428 4/20 0.68
CYP1A2 P05177 2/20 0.68
TSHR P16473 2/20 0.68
TP53 P04637 2/20 0.55
SLC2A1 P11166 1/20 0.55
CASP1 P29466 4/20 0.54
CASP7 P55210 4/20 0.54
EHMT2 Q96KQ7 1/20 0.49
KMT2A Q03164 6/20 0.49
MEN1 O00255 5/20 0.49
LMNA P02545 2/20 0.49
TERT O14746 1/20 0.49
ABCB11 O95342 1/20 0.49
THRB P10828 1/20 0.49
BLM P54132 1/20 0.49
MAPT P10636 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19983503 0.84 ALDH1A1 (0.67) ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD
SCHEMBL3645761 0.82 MAOB (0.51) ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD
SCHEMBL1043638 0.82 KDM4E (0.65) ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD
SCHEMBL3267333 0.82 PDE3B (0.54) ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD
SCHEMBL21173411 0.81 ALDH1A1 (0.68) ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD
SCHEMBL439655 0.81 ALDH1A1 (0.80) ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD
SCHEMBL2908071 0.81 KDM4E (0.59) ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD
SCHEMBL21173382 0.80 ALDH1A1 (0.62) ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD
SCHEMBL10899393 0.80 SMN1; SMN2 (0.62) ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD
SCHEMBL21707866 0.79 HSD17B10 (0.54) ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0124752-B1 MIXTURES OF SUBSTANCES WITH GROWTH AND OUTPUT ACCELERATING EFFECT AS WELL AS FEED AND WATERING LIQUIDS WHICH CONTAIN LOW AMOUNTS OF THESE MIXTURES BASF Aktiengesellschaft (DE) 1986-07-16 EP claimed
EP-0065192-B1 GROWTH-PROMOTING FODDER OR DRINKING LIQUID BASF Aktiengesellschaft (DE) 1984-02-01 EP claimed
US-4616016-A MIXTURE OF QUINALDINES, QUINOLINES, CYCLOHEXENE AMINOREDUCTONES BASF AKTIENGESELLSCHAFT (DE) 1986-10-07 US disclosed
EP-0124752-B1 MIXTURES OF SUBSTANCES WITH GROWTH AND OUTPUT ACCELERATING EFFECT AS WELL AS FEED AND WATERING LIQUIDS WHICH CONTAIN LOW AMOUNTS OF THESE MIXTURES BASF Aktiengesellschaft (DE) 1986-07-16 EP disclosed
EP-0124752-A1 Mixtures of substances with growth and output accelerating effect as well as feed and watering liquids which contain low amounts of these mixtures BASF Aktiengesellschaft (DE) 1984-11-14 EP disclosed