SCHEMBL10901475

SCHEMBL10901475

NC(=O)CCNC(=O)[C@@H](N)CO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 1/20 0.40
DPP7 Q9UHL4 2/20 0.39
KMT2A Q03164 2/20 0.39
ALOX15 P16050 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
RRM1 P23921 1/20 0.36
DPP4 P27487 1/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36
TLR2 O60603 1/20 0.36
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
FUCA1 P04066 1/20 0.35
GNAI3 P08754 1/20 0.34
GNAO1 P09471 1/20 0.34
GNAI1 P63096 1/20 0.34
ANPEP P15144 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12143787 0.80 USP2 (0.56) DPP7KMT2ARRM1TLR2MEN1
SCHEMBL8894805 0.78 DPP7 (0.47) DPP7KMT2AALOX15RRM1TLR2
SCHEMBL31618964 0.77 ECE1 (0.44) ECE1DPP7
SCHEMBL20233949 0.77 ECE1 (0.49) ECE1DPP7KMT2AALOX15BLM
SCHEMBL10070125 0.77 DPP7 (0.53) DPP7RRM1TLR2USP2FUCA1
SCHEMBL8735097 0.76 GNAI3 (0.62) DPP7RRM1DPP8DPP9TLR2
SCHEMBL13444714 0.76 DPP7 (0.53) ECE1DPP7KMT2AALOX15BLM
SCHEMBL3891772 0.76 ECE1 (0.43) ECE1DPP7KMT2AALOX15BLM
SCHEMBL10017680 0.75 DPP7 (0.43) DPP7RRM1USP2ALDH1A1FUCA1
SCHEMBL18820823 0.75 DPP7 (0.39) DPP7KMT2ARRM1TLR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4572894-A USING AMINOACYL-TRNA SYNTHETASE AS CONDENSING AGENT Imahori, Kazutomo (JP) 1986-02-25 US disclosed
EP-0086053-A1 Process for synthesizing peptides or peptide derivatives Imahori, Kazutomo (JP) 1983-08-17 EP disclosed