Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.51 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901907 | 0.93 | OPRM1 (0.48) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL17439162 | 0.92 | OPRM1 (0.49) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL2778544 | 0.89 | F2 (0.57) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL6497247 | 0.89 | F2 (0.57) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL2778546 | 0.89 | F2 (0.57) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL2119635 | 0.89 | F2 (0.57) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL6850160 | 0.89 | F2 (0.57) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL11278226 | 0.89 | OPRM1 (0.47) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL24195743 | 0.89 | OPRM1 (0.52) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL29610294 | 0.88 | OPRM1 (0.54) | OPRM1OPRD1OPRK1NPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563305-A | QUANTITATIVE ANALYSIS | UNIVERSITY OF MIAMI (US) | 1986-01-07 | — | — | US | disclosed |
| EP-0056015-A1 | Radiolabelled substrates for assaying mammalian enzymes | Ryan, James Walter (US) | 1982-07-14 | — | — | EP | disclosed |