⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034749 | 0.81 | GRIK1 (0.42) | — | |
| SCHEMBL14780782 | 0.77 | — | — | |
| SCHEMBL28010130 | 0.74 | GRIK1 (0.37) | — | |
| SCHEMBL28575140 | 0.74 | GRIK1 (0.37) | — | |
| SCHEMBL1029946 | 0.74 | GRIK1 (0.37) | — | |
| SCHEMBL7073739 | 0.74 | PPARA (0.42) | — | |
| SCHEMBL17800996 | 0.72 | GRIK1 (0.36) | — | |
| SCHEMBL3259337 | 0.72 | CPA1 (0.39) | — | |
| SCHEMBL10903021 | 0.72 | SRR (0.39) | — | |
| SCHEMBL21765482 | 0.72 | SRR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100900-B1 | NOVEL (3.2.0.) BICYCLOHEPTANONE OXIME ETHERS WITH VALUABLE THERAPEUTIC PROPERTIES | SYNTEX (U.S.A.) INC. (US) | 1986-02-05 | — | — | EP | disclosed |
| US-4552898-A | CARDIOVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-11-12 | — | — | US | disclosed |
| EP-0100900-A1 | Novel (3.2.0.) bicycloheptanone oxime ethers with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4423068-A | (3.2.0) Bicycloheptanone oxime ethers with therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1983-12-27 | — | — | US | disclosed |