SRR — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Aminooxyphenylpropionate (SCHEMBL1401589)	1.00	4/20
Aminooxyphenylpropionate (SCHEMBL1520985)	1.00	4/20
Aminooxyphenylpropionate (SCHEMBL1357763)	0.96	4/20
SCHEMBL288435	0.73	4/20
SCHEMBL2336410	0.55	4/20
SCHEMBL720353	0.54	4/20
SCHEMBL720354	0.54	4/20
SCHEMBL1368490	0.54	4/20
SCHEMBL392334	0.50	4/20
SCHEMBL392336	0.50	4/20
SCHEMBL2517934	0.70	3/20
SCHEMBL2501988	0.56	3/20
SCHEMBL2501991	0.56	3/20
SCHEMBL757308	0.53	3/20
SCHEMBL1094834	0.53	3/20
SCHEMBL1094835	0.53	3/20
SCHEMBL375857	0.51	3/20
SCHEMBL2040433	0.44	3/20
SCHEMBL1136238	0.44	3/20
SCHEMBL1486321	0.62	2/20

Clinical trials — most relevant to SRR by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Statin and Ezetimibe Association on Kinetics of Artificial Chilomicrons	PHASE4	COMPLETED
The Effect of Q10 and Selen Supplement on Muscular Adverse Events in Statin Therapy	PHASE4	COMPLETED
Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis	PHASE2	UNKNOWN
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC	PHASE2	COMPLETED
LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Hormone Sensitive Prostate Cancer	PHASE2	COMPLETED
Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer	PHASE2	COMPLETED
Efavirenz for Patients With Alzheimer's Disease	PHASE1	COMPLETED
Safety, Tolerability and Pharmacokinetics of Benfo-Oxythiamine (B-OT) in Healthy Volunteers	PHASE1	COMPLETED
5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy	nan	RECRUITING
Epidemiology of Atherosclerosis	nan	COMPLETED
Macrophage Migration Inhibitory Factor (MIF)- Cardiac Surgery	nan	COMPLETED
Mechanisms of Glucose Lowering Effect of Colesevelam HCl	nan	COMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)	nan	UNKNOWN
Proof of Concept Creatine Supplementation for Homocystinuria Study	nan	ACTIVE_NOT_RECRUITING
Plant-based Diets and Body Weight and Selected Metabolic Parameters Management in Obese Patients.	nan	COMPLETED
Family Patterns in Resting Metabolic Rate Between Parents and Adult Children	nan	NOT_YET_RECRUITING
Polycystic Ovary Syndrome in Type 1 Diabetes	nan	NOT_YET_RECRUITING
Pattern of Gene Expression in Adipose Tissue From Patients With Cushing Syndrome	nan	COMPLETED
Role and Interactions of Adenosine, Receptors, Methionine Cycle Nutritional, Metabolic and Genetic Determinants in the Onset of Atrial Fibrillation in Normal Heart	nan	UNKNOWN
Sex Hormones and Blood PCSK9 Levels	nan	COMPLETED
Individualized Antiretroviral Therapy	nan	COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Vulvodynia: Identification of Potential Relevant Biomarkers	nan	COMPLETED
Pharmacogenetic Determinants Of Treatment Response In Children	nan	RECRUITING
Statin Therapy and COVID-19 Infection	nan	COMPLETED
Influence of WNT4 VEZT FSHB and SIRT1 SNPs in Endometriosis: a Case Control Study of the Sardinian Population	nan	UNKNOWN
Pharmacogenomics of Antidepressant Response in Children and Adolescents	nan	COMPLETED
Influence of Simvastatin on Apolipoprotein B-100 (apoB-100) Secretion	nan	COMPLETED
Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-Acquired Pneumonia	nan	UNKNOWN
Androgens and NAFLD Longitudinal Cohort Study	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a SRR binder may also engage these)

Protein	Name	Similarity
Q9QZX7	—	1.000	Q9QZX7 →
Q76EQ0	—	0.999	Q76EQ0 →
A0JNI4	—	0.997	A0JNI4 →
Q2PGG3	—	0.994	Q2PGG3 →
A2XWA9	—	0.987	A2XWA9 →
Q7XSN8	—	0.985	Q7XSN8 →
P46794	—	0.983	P46794 →
B5VKE8	—	0.983	B5VKE8 →
Q1KLZ1	—	0.982	Q1KLZ1 →
P25379	—	0.982	P25379 →
Q7A5L8	—	0.981	Q7A5L8 →
P50867	—	0.981	P50867 →
A6ZVB1	—	0.981	A6ZVB1 →
P11954	—	0.981	P11954 →
C8ZAU6	—	0.981	C8ZAU6 →
Q54HH2	—	0.981	Q54HH2 →
P0AGF7	—	0.980	P0AGF7 →
P38076	—	0.980	P38076 →
O23735	—	0.980	O23735 →
P32260	—	0.980	P32260 →
B3LU13	—	0.980	B3LU13 →
P0CF23	—	0.979	P0CF23 →
P47998	—	0.979	P47998 →
A8NEP3	—	0.979	A8NEP3 →
P00931	—	0.979	P00931 →
Q2YY67	—	0.978	Q2YY67 →
P13228	—	0.978	P13228 →
O59791	—	0.978	O59791 →
Q59966	—	0.978	Q59966 →
P80608	—	0.978	P80608 →