Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 5/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10904118 | 0.84 | KMT2A (0.46) | XPNPEP1KMT2ADPP4DPP8DPP9 | |
| SCHEMBL10903577 | 0.83 | XPNPEP1 (0.40) | XPNPEP1KMT2ADPP4DPP8DPP9 | |
| SCHEMBL10903580 | 0.83 | XPNPEP1 (0.40) | XPNPEP1KMT2ADPP4DPP8DPP9 | |
| SCHEMBL10903563 | 0.79 | ACE2 (0.56) | KMT2ALMNAACE2L3MBTL1KDM4E | |
| SCHEMBL10903562 | 0.79 | ACE2 (0.56) | KMT2ALMNAACE2L3MBTL1KDM4E | |
| SCHEMBL10903553 | 0.77 | XPNPEP1 (0.44) | XPNPEP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL10903555 | 0.77 | XPNPEP1 (0.44) | XPNPEP1DPP4DPP8DPP9DPP7 | |
| SCHEMBL14856704 | 0.77 | HSP90AA1 (0.43) | — | |
| SCHEMBL14856478 | 0.77 | HSP90AA1 (0.43) | — | |
| SCHEMBL14856477 | 0.77 | HSP90AA1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596819-A | Antidepressive agents | WARNER-LAMBERT COMPANY (US) | 1986-06-24 | — | — | US | disclosed |