Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | HHAT | Q5VTY9 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901947 | 0.83 | ACE (0.57) | ACEMTNR1BHHATMEN1MAPT | |
| SCHEMBL10901930 | 0.83 | ACE (0.57) | ACEMTNR1BHHATMEN1MAPT | |
| SCHEMBL16111164 | 0.83 | ACE (0.68) | ACEMTNR1BHHATKEAP1 | |
| SCHEMBL22461193 | 0.82 | HHAT (0.57) | HHATPRCPCYP2D6 | |
| SCHEMBL22461199 | 0.82 | HHAT (0.57) | HHATPRCPCYP2D6 | |
| SCHEMBL24490384 | 0.81 | DRD1 (0.55) | ACEMTNR1BHHATMEN1MAPT | |
| SCHEMBL24489981 | 0.79 | ACE (0.40) | ACEMTNR1BHHATMEN1MAPT | |
| SCHEMBL24490312 | 0.79 | DRD1 (0.44) | ACEMTNR1BHHATMEN1MAPT | |
| SCHEMBL24490306 | 0.79 | DRD1 (0.44) | ACEMTNR1BHHATMEN1MAPT | |
| SCHEMBL19953529 | 0.78 | ACE (0.61) | ACEMTNR1BKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4594199-A | Method for making phosphinic acid intermediates | E. R. SQUIBB & SONS, INC. (US) | 1986-06-10 | — | — | US | disclosed |