Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10904485 | 0.98 | GPR84 (0.50) | GPR84FFAR1FFAR4NFKB1PSMD14 | |
| SCHEMBL10903731 | 0.98 | GPR84 (0.50) | GPR84FFAR1FFAR4NFKB1PSMD14 | |
| SCHEMBL10901955 | 0.93 | — | — | |
| SCHEMBL28116791 | 0.82 | — | — | |
| SCHEMBL11193977 | 0.82 | FFAR1 (0.56) | GPR84FFAR1FFAR4NFKB1TRPA1 | |
| SCHEMBL11193975 | 0.82 | FFAR1 (0.56) | GPR84FFAR1FFAR4NFKB1TRPA1 | |
| SCHEMBL449788 | 0.81 | FFAR1 (0.64) | GPR84FFAR1FFAR4NFKB1PSMD14 | |
| SCHEMBL449789 | 0.81 | FFAR1 (0.64) | GPR84FFAR1FFAR4NFKB1PSMD14 | |
| SCHEMBL9245478 | 0.80 | FFAR1 (0.58) | GPR84FFAR1FFAR4NFKB1TRPA1 | |
| SCHEMBL6138956 | 0.79 | GPR84 (0.50) | GPR84FFAR1FFAR4NFKB1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290878-A | NOVEL FERROPORTIN INHIBITORS | 威佛（国际）股份公司 | 2018-07-17 | — | — | CN | disclosed |
| US-4590291-A | Thrombin inhibitory new dihydroxybenzene ether derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-20 | — | — | US | disclosed |
| EP-0068250-A1 | Dioxybenzene ether derivatives, pharmaceutical compositions containing them, process for the preparation thereof and their use | BAYER AG (DE) | 1983-01-05 | — | — | EP | disclosed |