Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Anthraquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | CDC25B | P30305 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | S100A4 | P26447 | 4/20 | 0.55 |
| ▸ | APAF1 | O14727 | 3/20 | 0.55 |
| ▸ | TDP2 | O95551 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 9,10-Phenanthrenequinone SCHEMBL28567802 | 0.92 | S100A4 (0.68) | MEN1KMT2ACDC25BRAB9ASMN1; SMN2 | |
| Anthraquinone SCHEMBL616605 | 0.86 | MEN1 (0.71) | MEN1KMT2ACDC25BRAB9ASMN1; SMN2 | |
| Anthraquinone SCHEMBL11302120 | 0.85 | CDC25B (0.80) | MEN1KMT2ACDC25BRAB9ASMN1; SMN2 | |
| Anthraquinone SCHEMBL28215858 | 0.83 | CDC25B (0.67) | MEN1KMT2ACDC25BRAB9ASMN1; SMN2 | |
| Anthraquinone SCHEMBL28758919 | 0.83 | MEN1 (0.67) | MEN1KMT2ACDC25BRAB9ASMN1; SMN2 | |
| Anthraquinone SCHEMBL430600 | 0.83 | MEN1 (0.67) | MEN1KMT2ACDC25BRAB9ASMN1; SMN2 | |
| Anthraquinone SCHEMBL7856851 | 0.82 | MEN1 (0.57) | MEN1KMT2ACDC25BRAB9ASMN1; SMN2 | |
| Anthraquinone SCHEMBL17747127 | 0.82 | CDC25B (0.57) | MEN1KMT2ACDC25BRAB9ASMN1; SMN2 | |
| Anthraquinone SCHEMBL27767988 | 0.82 | MEN1 (0.57) | MEN1KMT2ACDC25BRAB9ASMN1; SMN2 | |
| Anthraquinone SCHEMBL5958714 | 0.82 | CDC25B (0.86) | MEN1KMT2ACDC25BRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113509751-B | Extraction-back extraction system based on alkanol eutectic solvent and application thereof | 武汉大学 | 2022-07-19 | — | — | CN | disclosed |
| US-11236207-B2 | Solid state electrodes and sensors | PARKER HANNIFIN CORP (US) | 2022-02-01 | — | — | US | disclosed |
| CN-113509751-A | Extraction-back extraction system based on alkanol eutectic solvent and application thereof | 武汉大学 | 2021-10-19 | — | — | CN | disclosed |
| US-20200207928-A1 | SOLID STATE ELECTRODES AND SENSORS | PARKER HANNIFIN CORP (US) | 2020-07-02 | — | — | US | disclosed |
| US-10538635-B2 | Solid state electrodes and sensors | PARKER INTANGIBLES LLC | 2020-01-21 | — | — | US | disclosed |
| EP-3155408-B1 | SOLID STATE ELECTRODES AND SENSORS | PARKER HANNIFIN CORP (US) | 2019-05-22 | — | — | EP | disclosed |
| CN-106159195-B | A kind of battery core and the lithium ion battery comprising the battery core | 比亚迪股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-3155408-A1 | SOLID STATE ELECTRODES AND SENSORS | Parker-Hannifin Corporation (US) | 2017-04-19 | — | — | EP | disclosed |
| US-20170101513-A1 | SOLID STATE ELECTRODES AND SENSORS | Parker-Hannifin Coporation (US) | 2017-04-13 | — | — | US | disclosed |
| WO-2015191924-A1 | SOLID STATE ELECTRODES AND SENSORS | SENOVA SYSTEMS, INC. (US) | 2015-12-17 | — | — | WO | disclosed |
| CN-103374246-A | Flexible uv-curable coating compositions | SDC TECHNOLOGIES INC | 2013-10-30 | — | — | CN | disclosed |
| US-4597830-A | FREE OF SODIUM HYDROXIDE AND SULFIDES | THE UNIVERSITY OF ALABAMA (US) | 1986-07-01 | — | — | US | disclosed |