S100A4

Protein S100-A4 · P26447 · S100A4 on Sugi Atlas →

29,197 patent compounds predicted against S100A4, 16,957 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Zorubicin (SCHEMBL168293)	0.61	8/20
SCHEMBL380061	0.88	7/20
Zorubicin (SCHEMBL8231)	0.84	7/20
Zorubicin (SCHEMBL8232)	0.84	7/20
SCHEMBL162675	0.82	7/20
Esorubicin (SCHEMBL3864)	0.81	7/20
Daunomycinone (SCHEMBL118279)	0.66	7/20
Daunomycinone (SCHEMBL118280)	0.66	7/20
Epirubicin (SCHEMBL3165)	1.00	6/20
Doxorubicin (SCHEMBL3242)	1.00	6/20
Doxorubicin (SCHEMBL57097)	1.00	6/20
Doxorubicin (SCHEMBL177976)	1.00	6/20
Doxorubicin (SCHEMBL317301)	1.00	6/20
Epirubicin (SCHEMBL317302)	1.00	6/20
SCHEMBL248564	0.85	6/20
SCHEMBL319890	0.84	6/20
Hydrochloric Acid (SCHEMBL331063)	0.84	6/20
Zorubicin (SCHEMBL4023)	0.83	6/20
Zorubicin (SCHEMBL4024)	0.83	6/20
Pirarubicin (SCHEMBL99651)	0.79	6/20

Clinical trials — most relevant to S100A4 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Serum Calprotectin Level in Patients With Rheumatoid Arthritis and Osteoarthritis	PHASE4	UNKNOWN
Dexmedetomidine and Magnesium Sulfate in the Reduction Cognitive Dysfunction in Geriatrics	PHASE1	RECRUITING
Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival	PHASE1	UNKNOWN
S100A8 in Serum and Urine as a New Biomarker in Lupus Nephritis	nan	COMPLETED
Neurological Prognostication of Patients in Therapeutic Hypothermia After Cardiac Arrest	nan	COMPLETED
Urine Concentration of S100B in Extremely Premature Infants	nan	COMPLETED
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life	nan	COMPLETED
S100 Protein in Minor/Mild Traumatic Brain Injury	nan	COMPLETED
Protein S100B Versus Neutrophils/Lymphocytes Ratio in Early Prediction of Brain Injury	nan	COMPLETED
Evaluation of s100β, NSE and GFAP Levels in Renal Transplantation	nan	COMPLETED
Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment	nan	RECRUITING
S100A8/A9 and Innate Immunity in Liver Disease	nan	UNKNOWN
S100β and Neuron Specific Enolase Levels in Liver Transplantation	nan	COMPLETED
S100B in the Care of Non-traumatic Headaches in the Emergency Department	nan	COMPLETED
Diagnostic Performance of the S100B Protein in the Prognosis of Patients With Mild Head Trauma With Risk of Complications in Patients Over 65 Years Old.	nan	UNKNOWN
GRINCH: Groningen Initiative on Reference Intervals in Children	nan	COMPLETED
Using Routine Inflammatory and Metabolic Blood Tests (Bedside Included) to Predict Brain Injury in Children After Minor Head Trauma	nan	NOT_YET_RECRUITING
Role of Concentration of Biomarkers S100B and NSE in Serum in Mild and Moderate Head Trauma	nan	UNKNOWN
Diagnosis of Sport-related Concussion Using Urine Metabolites	nan	COMPLETED
Sepsis Associated Encephalopathy (SAE) Biomarkers	nan	ACTIVE_NOT_RECRUITING
Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunction and Delirium	nan	COMPLETED
Interventional Study for Detection of Prognosis of Blood Based Biomarkers in Intracerebral Hemorrhage	nan	NOT_YET_RECRUITING
Predictive Model for the Occurrence of Cerebral Vasospasm Complicating Subarachnoid Haemorrhage by Combined Analysis of the Kinetics of a Panel of Biomarkers.	nan	COMPLETED
MD2, Cystatin C and DNA Methylation Tags as Serum Biomarkers for POCD.	nan	UNKNOWN
The Clinical Utility of Fecal Caprotectin and Lactoferrin in Patients Undergoing Capsular Endoscopy	nan	UNKNOWN
Single-center Transversal Observational Study on the Evaluation of S100B Changes in Subjects Attending the Emergency Department With Head Trauma	nan	RECRUITING
Effect of Intraoperative Sedation on PND in Elderly Patients	nan	UNKNOWN
OptiCal Study -Optimizing Fecal Calprotectin Monitoring: a Clinical Study Comparing CalproLab Against PhiCal and Evaluating Its Association With the Gut Microbiome	nan	COMPLETED
Study Assessing Evaluation of the Interest of Serum S100B Protein Determination in the Management of Pediatric Mild Traumatic Brain Injury	nan	COMPLETED
Protein S100 Beta as a Predictor of Resuscitation Outcome	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a S100A4 binder may also engage these)

Protein	Name	Similarity
P05942	—	1.000	P05942 →
Q9TV56	—	1.000	Q9TV56 →
P35466	—	1.000	P35466 →
P07091	—	1.000	P07091 →
P10462	—	0.992	P10462 →
P29034	—	0.989	P29034 →
P30801	—	0.986	P30801 →
Q503K9	—	0.984	Q503K9 →
S100P	Protein S100-P	0.982	landscape →
Q8WXG8	—	0.981	Q8WXG8 →
Q7LZT1	—	0.978	Q7LZT1 →
O77691	—	0.977	O77691 →
P35467	—	0.977	P35467 →
P04631	—	0.976	P04631 →
P50114	—	0.974	P50114 →
P27004	—	0.973	P27004 →
P02638	—	0.972	P02638 →
Q6YNR6	—	0.972	Q6YNR6 →
S100B	Protein S100-B	0.972	landscape →
P31151	—	0.972	P31151 →
P24479	—	0.972	P24479 →
Q98953	—	0.971	Q98953 →
Q5RC36	—	0.971	Q5RC36 →
P97352	—	0.971	P97352 →
P23297	—	0.971	P23297 →
P79105	—	0.971	P79105 →
P56565	—	0.971	P56565 →
P02639	—	0.971	P02639 →
Q28050	—	0.971	Q28050 →
P31725	—	0.970	P31725 →