Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14394146 | 0.87 | MEN1 (0.50) | NR1H2KMT2AMEN1MAPTLMNA | |
| SCHEMBL70958 | 0.86 | CA1 (0.55) | KMT2AMEN1MAPTLMNACA1 | |
| SCHEMBL12429542 | 0.83 | MEN1 (0.50) | NR1H2KMT2AMEN1MAPTLMNA | |
| SCHEMBL10977917 | 0.81 | NR1H2 (0.44) | NR1H2KMT2AMEN1MAPTLMNA | |
| SCHEMBL10710607 | 0.81 | NR1H2 (0.58) | NR1H2KMT2AMEN1MAPTLMNA | |
| SCHEMBL28246410 | 0.81 | NR1H2 (0.93) | NR1H2KMT2AMEN1MAPTLMNA | |
| SCHEMBL15184102 | 0.80 | LMNA (0.43) | NR1H2KMT2AMEN1MAPTLMNA | |
| SCHEMBL4801171 | 0.80 | NR1H2 (0.64) | NR1H2KMT2AMEN1MAPTLMNA | |
| SCHEMBL6543622 | 0.79 | CA1 (0.39) | NR1H2KMT2AMEN1MAPTLMNA | |
| SCHEMBL2754937 | 0.79 | ESR1 (0.43) | NR1H2KMT2AMEN1MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608430-A | ENGINEERING THERMOPLASTICS | GENERAL ELECTRIC COMPANY (US) | 1986-08-26 | — | — | US | disclosed |
| EP-0141096-A1 | Polyarylate compositions | GENERAL ELECTRIC COMPANY (US) | 1985-05-15 | — | — | EP | disclosed |
| EP-0133658-A2 | Flame retardant non-dripping polycarbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1985-03-06 | — | — | EP | disclosed |
| US-4490504-A | CONTAINING GLASS FIBERS, DIHYDRIC PHENOLS, AND THIUODIPHENOLS | GENERAL ELECTRIC COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4477647-A | FIREPROOF ENGINEERING THERMOPLASTICS | GENERAL ELECTRIC COMPANY (US) | 1984-10-16 | — | — | US | disclosed |