Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 10/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10902844 | 1.00 | STAT3 (0.41) | STAT3DPP4DPP8DPP9DPP7 | |
| SCHEMBL10903576 | 0.88 | KMT2A (0.38) | STAT3DPP4DPP8DPP9DPP7 | |
| SCHEMBL10903575 | 0.88 | KMT2A (0.38) | STAT3DPP4DPP8DPP9DPP7 | |
| SCHEMBL10903608 | 0.84 | KMT2A (0.46) | STAT3F2KMT2A | |
| SCHEMBL10903604 | 0.84 | KMT2A (0.46) | STAT3F2KMT2A | |
| SCHEMBL10904483 | 0.82 | CTRB1 (0.61) | STAT3KMT2A | |
| SCHEMBL10904486 | 0.82 | CTRB1 (0.61) | STAT3KMT2A | |
| SCHEMBL10903691 | 0.75 | KMT2A (0.37) | STAT3DPP4DPP8DPP9DPP7 | |
| SCHEMBL10903686 | 0.75 | KMT2A (0.37) | STAT3DPP4DPP8DPP9DPP7 | |
| SCHEMBL16529713 | 0.74 | ACE (0.44) | XIAPF2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596819-A | Antidepressive agents | WARNER-LAMBERT COMPANY (US) | 1986-06-24 | — | — | US | disclosed |