Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 9/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12369534 | 0.89 | CHRM2 (0.50) | BCHEACHEMAOBCHRM2CHRM4 | |
| SCHEMBL10901959 | 0.88 | ACHE (0.65) | BCHEACHEHTR2CMAOBMAOA | |
| SCHEMBL12369458 | 0.84 | F12 (0.48) | BCHEACHEMAOBCHRM2CHRM4 | |
| SCHEMBL10902287 | 0.81 | BCHE (0.65) | BCHEACHEMAOBCHRM2CHRM4 | |
| SCHEMBL10901732 | 0.81 | ACHE (0.65) | BCHEACHEHTR2CMAOBMAOA | |
| SCHEMBL30010802 | 0.81 | ACHE (0.65) | BCHEACHEHTR2CMAOBMAOA | |
| SCHEMBL10902517 | 0.81 | BCHE (0.65) | BCHEACHEMAOBCHRM2CHRM4 | |
| SCHEMBL2874836 | 0.81 | BCHE (0.59) | BCHEACHEHTR2CMAOBMAOA | |
| SCHEMBL3891708 | 0.81 | MAOB (0.61) | BCHEACHEHTR2CMAOBMAOA | |
| SCHEMBL10902488 | 0.80 | CHRM2 (0.53) | BCHEACHEMAOBCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | claimed |
| WO-2021030620-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |