Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23214242 | 0.87 | S1PR1 (0.50) | ALDH1A1S1PR1POLBLMNACYP3A4 | |
| SCHEMBL7819834 | 0.85 | HSD17B10 (0.50) | ALDH1A1S1PR1RAB9ACYP3A4NPC1 | |
| SCHEMBL17335676 | 0.80 | CTSD (0.49) | LMNACYP3A4MAPT | |
| SCHEMBL25124460 | 0.80 | CYP3A4 (0.50) | ALDH1A1S1PR1CYP3A4CYP2D6PORCN | |
| SCHEMBL9625793 | 0.78 | CYP2D6 (0.52) | S1PR1CYP3A4CYP2D6PORCNSMN1; SMN2 | |
| SCHEMBL10903934 | 0.78 | KCNK3 (0.54) | S1PR1RAB9APOLBLMNANPC1 | |
| SCHEMBL23239979 | 0.78 | CYP1A2 (0.53) | ALDH1A1S1PR1POLBLMNACYP3A4 | |
| SCHEMBL29716248 | 0.78 | CYP1A2 (0.53) | ALDH1A1S1PR1POLBLMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL9625800 | 0.78 | CYP2D6 (0.51) | S1PR1CYP3A4CYP2D6PORCNSMN1; SMN2 | |
| SCHEMBL10902008 | 0.78 | CYP3A4 (0.54) | ALDH1A1S1PR1CYP3A4CYP2D6FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4602031-A | Anti-depressant imidazoles, compositions and use | EISAI CO., LTD. (JP) | 1986-07-22 | — | — | US | disclosed |
| US-4533669-A | NONTOXIC | EISAI CO., LTD. (JP) | 1985-08-06 | — | — | US | disclosed |
| US-4402966-A | Acylaminophenyl imidazoles and anti-depressing agent containing the same | EISAI CO., LTD. (JP) | 1983-09-06 | — | — | US | disclosed |
| US-4301169-A | Novel imidazole compound and anti-depressing agent containing the same | EISAI CO., LTD. (JP) | 1981-11-17 | — | — | US | disclosed |