SCHEMBL10902860

SCHEMBL10902860

CCOP(=S)(Cl)NC(C)CC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10414472 0.83 TP53 (0.37) TP53TDP1
SCHEMBL10979294 0.82 TP53 (0.31) TP53TDP1
SCHEMBL10904562 0.81 MMP1 (0.32)
SCHEMBL10906741 0.75
SCHEMBL10875881 0.75
SCHEMBL11445676 0.73 MMP1 (0.34) TP53TDP1
Hydrochloric Acid SCHEMBL10931716 0.73 MMP1 (0.34) TP53TDP1
SCHEMBL11072575 0.73
SCHEMBL12207732 0.71 TSHR (0.42) TP53TDP1
SCHEMBL12207735 0.71 TSHR (0.42) TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4608367-A γ-Pyrone phosphoric ester derivatives and insecticidal and miticidal compositions thereof OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1986-08-26 US disclosed
US-4522817-A Phosphoramidothionates and fungicidal use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-06-11 US disclosed
EP-0089191-A2 Fungicidal composition comprising phosphoramidothionates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-09-21 EP disclosed
US-4320126-A INSECTICIDES, MITICIDES, NEMATOCIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-03-16 US disclosed
US-4308258-A Pyrimidin-4-yl-phosphorus esters and insecticidal, acaricidal or nematocidal compositions and methods using them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-12-29 US disclosed
US-4110440-A ARTHROPODICIDE, NEMATOCIDE NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1978-08-29 US disclosed