SCHEMBL10903164

SCHEMBL10903164

CCC(C)CNC(=O)CC(O)C(CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10903182 1.00 REN (0.58) REN
SCHEMBL10721002 1.00 REN (0.58) REN
SCHEMBL10720995 1.00 REN (0.58) REN
SCHEMBL10722789 0.98 REN (0.60) REN
SCHEMBL10722785 0.98 REN (0.60) REN
SCHEMBL10725385 0.95 REN (0.56) REN
SCHEMBL10725391 0.95 REN (0.56) REN
SCHEMBL10720920 0.94 REN (0.57) REN
SCHEMBL10720925 0.94 REN (0.57) REN
SCHEMBL10721168 0.94 REN (0.55) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0186977-A2 Renin-inhibitory dipeptides, their preparation and use SANKYO COMPANY LIMITED (JP) 1986-07-09 — — EP disclosed
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