SCHEMBL10904875

SCHEMBL10904875

Oc1c(Cc2ccccc2)cc(CP(O)(=S)S)cc1Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.46
PTPN2 P17706 1/20 0.46
PTPN6 P29350 1/20 0.46
BCL2 P10415 1/20 0.46
BCL2L1 Q07817 1/20 0.46
ALOX5 P09917 1/20 0.41
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
KMT2A Q03164 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6681829 0.80 HPGD (0.46) HPGD
SCHEMBL10905920 0.80 PTPN1 (0.53) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL9174306 0.77 PTPN1 (0.70) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL9804555 0.77 PTPN1 (0.70) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL10907320 0.75 BCL2 (0.55) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL11209438 0.75 PTPN1 (0.68) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL10905032 0.73 BCL2 (0.57) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL10905271 0.73 BCL2 (0.57) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL10903393 0.73 BCL2 (0.52) PTPN1PTPN2PTPN6BCL2BCL2L1
SCHEMBL10905203 0.72 BCL2 (0.55) PTPN1PTPN2PTPN6BCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4613642-A ANTIOXIDANTS FOR POLYOLEFINS ETHYL CORPORATION (US) 1986-09-23 US disclosed