Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907963 | 0.86 | SLC6A2 (0.36) | LMNASLC6A2SLC6A4POLBPTGS1 | |
| SCHEMBL10905946 | 0.85 | HPGD (0.33) | HPGDHDAC1 | |
| SCHEMBL10905771 | 0.84 | GRIN2D (0.38) | LMNAPOLBHPGDPTGS1PTGS2 | |
| SCHEMBL10906944 | 0.84 | ABL1 (0.33) | LMNASLC6A2SLC6A4ABL1 | |
| SCHEMBL10907876 | 0.83 | HPGD (0.42) | HPGD | |
| SCHEMBL10907002 | 0.82 | SCN9A (0.31) | SLC6A2SLC6A4ABL1 | |
| SCHEMBL10905924 | 0.82 | HPGD (0.35) | LMNAHPGD | |
| SCHEMBL10907691 | 0.81 | SLC6A2 (0.33) | LMNASLC6A2SLC6A4POLBABL1 | |
| SCHEMBL10905456 | 0.81 | HPGD (0.40) | LMNAHPGD | |
| SCHEMBL10906936 | 0.78 | SLC6A4 (0.38) | SLC6A2SLC6A4POLBPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |