Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903777 | 0.87 | SLC6A2 (0.31) | SLC6A2SLC6A4 | |
| SCHEMBL10906944 | 0.86 | ABL1 (0.33) | SCN9AABL1SLC6A2SLC6A4 | |
| SCHEMBL10907691 | 0.85 | SLC6A2 (0.33) | SCN9AABL1SLC6A2SLC6A4 | |
| SCHEMBL10906685 | 0.83 | — | — | |
| SCHEMBL10905604 | 0.82 | LMNA (0.36) | ABL1SLC6A2SLC6A4 | |
| SCHEMBL10907705 | 0.81 | KMT2A (0.36) | SLC6A2SLC6A4 | |
| SCHEMBL10907913 | 0.81 | TSHR (0.42) | — | |
| SCHEMBL10907009 | 0.80 | POLB (0.40) | SLC6A2SLC6A4 | |
| SCHEMBL10907708 | 0.76 | HDAC4 (0.32) | — | |
| SCHEMBL10905715 | 0.75 | HDAC4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |