Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906692 | 0.87 | MEN1 (0.39) | ALDH1A1GAA | |
| SCHEMBL10903853 | 0.86 | PTPN1 (0.35) | POLB | |
| SCHEMBL10903836 | 0.86 | TSHR (0.36) | POLBALDH1A1GAA | |
| SCHEMBL10907009 | 0.85 | POLB (0.40) | POLBGAA | |
| SCHEMBL10905715 | 0.85 | HDAC4 (0.30) | — | |
| SCHEMBL10905849 | 0.85 | POLB (0.37) | POLBTNFSF11 | |
| SCHEMBL10905816 | 0.84 | ALDH1A1 (0.32) | ALDH1A1GAA | |
| SCHEMBL10905924 | 0.83 | HPGD (0.35) | ALDH1A1GAA | |
| SCHEMBL10906944 | 0.82 | ABL1 (0.33) | — | |
| SCHEMBL10903864 | 0.80 | ALDH1A1 (0.34) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |