Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348790 | 0.81 | ALDH1A1 (0.37) | ALDH1A1TSHRHTT | |
| SCHEMBL15105913 | 0.78 | TSHR (0.35) | ALDH1A1TSHRHTT | |
| SCHEMBL8349586 | 0.73 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL10903315 | 0.72 | ALDH1A1 (0.34) | ALDH1A1TSHRHTT | |
| SCHEMBL10532479 | 0.72 | TSHR (0.32) | ALDH1A1TSHR | |
| SCHEMBL7837509 | 0.72 | EGLN1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL7601884 | 0.71 | — | — | |
| SCHEMBL503383 | 0.71 | — | — | |
| SCHEMBL503376 | 0.71 | — | — | |
| SCHEMBL371079 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100900-B1 | NOVEL (3.2.0.) BICYCLOHEPTANONE OXIME ETHERS WITH VALUABLE THERAPEUTIC PROPERTIES | SYNTEX (U.S.A.) INC. (US) | 1986-02-05 | — | — | EP | disclosed |
| US-4552898-A | CARDIOVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-11-12 | — | — | US | disclosed |
| EP-0100900-A1 | Novel (3.2.0.) bicycloheptanone oxime ethers with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4423068-A | (3.2.0) Bicycloheptanone oxime ethers with therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1983-12-27 | — | — | US | disclosed |