Styrene

Styrene

SCHEMBL10906129

C=CC(=O)OCCC.C=CC(=O)OCCO.C=Cc1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.54
THRB P10828 4/20 0.50
HPGD P15428 1/20 0.46
LMNA P02545 1/20 0.44
ALDH1A1 P00352 6/20 0.41
HCAR2 Q8TDS4 1/20 0.39
APP P05067 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
AKR1B10 O60218 1/20 0.38
AKR1B1 P15121 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
THRA P10827 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL379434 0.94 THRB (0.55) TSHRTHRBHPGDLMNAALDH1A1
Styrene SCHEMBL6236168 0.93 TSHR (0.63) TSHRTHRBHPGDLMNAALDH1A1
Styrene SCHEMBL10906555 0.92 TSHR (0.59) TSHRTHRBHPGDLMNAALDH1A1
Styrene SCHEMBL10906543 0.91 TSHR (0.45) TSHRTHRBHPGDLMNAALDH1A1
Styrene SCHEMBL28806445 0.91 THRB (0.53) TSHRTHRBHPGDLMNAALDH1A1
Styrene SCHEMBL17746691 0.91 THRB (0.53) TSHRTHRBHPGDLMNAALDH1A1
Styrene SCHEMBL18818305 0.91 TSHR (0.61) TSHRTHRBHPGDLMNAALDH1A1
Styrene SCHEMBL10970647 0.90 TSHR (0.59) TSHRTHRBHPGDLMNAALDH1A1
Styrene SCHEMBL28739829 0.87 THRB (0.49) TSHRTHRBHPGDLMNAALDH1A1
Styrene SCHEMBL10905441 0.87 TSHR (0.48) TSHRTHRBHPGDLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4571379-A ACRYLATE TERPOLYMER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-02-18 US disclosed