Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.80 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.80 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.69 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | NSD2 | O96028 | 2/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | FGF1 | P05230 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905524 | 0.94 | CASP6 (0.70) | CASP6CTDSP1PRMT1NT5EENPP2 | |
| SCHEMBL11342001 | 0.92 | PRMT1 (0.82) | CASP6CTDSP1PRMT1NT5EENPP2 | |
| SCHEMBL10905567 | 0.91 | CASP6 (0.67) | CASP6CTDSP1PRMT1NT5EENPP2 | |
| SCHEMBL27648929 | 0.91 | CASP6 (0.81) | CASP6CTDSP1PRMT1NT5EENPP2 | |
| SCHEMBL8416221 | 0.91 | PRMT1 (0.83) | CASP6CTDSP1PRMT1NT5EENPP2 | |
| SCHEMBL30646175 | 0.90 | CASP6 (0.98) | CASP6CTDSP1PRMT1NT5EENPP2 | |
| SCHEMBL14413308 | 0.90 | CASP6 (0.98) | CASP6CTDSP1PRMT1NT5EENPP2 | |
| SCHEMBL10909338 | 0.89 | CASP6 (0.67) | CASP6CTDSP1PRMT1NT5EENPP2 | |
| SCHEMBL29495050 | 0.89 | CASP6 (1.00) | CASP6CTDSP1PRMT1NT5EENPP2 | |
| SCHEMBL7890022 | 0.89 | CASP6 (0.78) | CASP6CTDSP1PRMT1NT5EENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |