Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905770 | 0.90 | BRD4 (0.45) | PTPN1FFAR4SMN1; SMN2BRD4LMNA | |
| SCHEMBL10903817 | 0.88 | PTPN1 (0.41) | PTPN1FFAR4SMN1; SMN2BRD4KMT2A | |
| SCHEMBL10905670 | 0.86 | MAPT (0.44) | PTPN1FFAR4SMN1; SMN2BRD4MEN1 | |
| SCHEMBL10903906 | 0.85 | BRD4 (0.44) | FFAR4SMN1; SMN2BRD4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10906203 | 0.85 | MAPT (0.44) | PTPN1FFAR4SMN1; SMN2BRD4MEN1 | |
| SCHEMBL10905417 | 0.83 | MRGPRX4 (0.44) | FFAR4SMN1; SMN2MEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL10907709 | 0.82 | MRGPRX4 (0.44) | FFAR4SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL10907003 | 0.82 | CLCN2 (0.42) | SMN1; SMN2BRD4MEN1KMT2ALMNA | |
| SCHEMBL10906376 | 0.82 | TSHR (0.37) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL10906934 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2BRD4MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |