Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903715 | 0.86 | CLCN2 (0.55) | CLCN2KDM4ECHRM4CHRM3BRD4 | |
| SCHEMBL10903888 | 0.86 | BRD4 (0.43) | CLCN2KDM4ECHRM4CHRM3MEN1 | |
| SCHEMBL10907005 | 0.84 | NPC1 (0.46) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL10907022 | 0.82 | LMNA (0.40) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL10907692 | 0.82 | PTPN1 (0.44) | SMN1; SMN2MEN1KMT2ABRD4MCL1 | |
| SCHEMBL10906934 | 0.80 | SMN1; SMN2 (0.42) | KDM4ESMN1; SMN2MEN1KMT2ABRD4 | |
| SCHEMBL10903906 | 0.80 | BRD4 (0.44) | SMN1; SMN2MEN1KMT2ABRD4MCL1 | |
| SCHEMBL10905809 | 0.78 | BRD4 (0.42) | SMN1; SMN2MEN1KMT2ABRD4PPIA | |
| SCHEMBL10903742 | 0.78 | SLC6A5 (0.42) | KDM4ESMN1; SMN2MEN1KMT2ABRD4 | |
| SCHEMBL10905431 | 0.77 | KDM4E (0.41) | CLCN2KDM4ECHRM4CHRM3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |