Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.34 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4406750 | 0.80 | CSNK2A1 (0.36) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL1560836 | 0.67 | PARP1 (0.51) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL17819122 | 0.64 | DAO (0.39) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL5441685 | 0.64 | KDM4E (0.42) | MEN1KMT2AALDH1A1NSD2CASP6 | |
| SCHEMBL5426665 | 0.63 | NSD2 (0.46) | MEN1KMT2AALDH1A1NSD2CASP6 | |
| SCHEMBL1551529 | 0.63 | CSNK2A1 (0.41) | CSNK2A1 | |
| SCHEMBL1559735 | 0.60 | PARP1 (0.44) | ALDH1A1KDM4EMAPTTDP1THRB | |
| SCHEMBL8278863 | 0.60 | MAPK1 (0.43) | ALDH1A1MAPK1KDM4EMAPTL3MBTL1 | |
| SCHEMBL10842207 | 0.60 | — | — | |
| SCHEMBL4379221 | 0.59 | KMT2A (0.45) | MEN1KMT2AALDH1A1MAPK1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059368-A2 | FUSED 2-AMINO PYRIMIDINE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER | PFIZER PRODUCTS INC. (US) | 2008-05-22 | — | — | WO | disclosed |
| US-4617258-A | WATER SOLUBLE GROUP 8 COMPOUNDS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-10-14 | — | — | US | disclosed |
| US-4477561-A | PLATIUM, DALLADIUM, RHODIUM, IRIDIUM AND OSMIUM SALTS; LIGHT SENSITIVE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| EP-0091788-A2 | Silver halide photographic material | KONICA CORPORATION (JP) | 1983-10-19 | — | — | EP | disclosed |
| EP-0087880-A2 | Silver halide photographic material | KONICA CORPORATION (JP) | 1983-09-07 | — | — | EP | disclosed |