Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560085 | 0.81 | GDA (0.53) | KMT2AMEN1GDACYP3A4PMP22 | |
| SCHEMBL10998 | 0.81 | GDA (0.53) | KMT2AMEN1GDACYP3A4PMP22 | |
| SCHEMBL5431750 | 0.79 | GAA (0.48) | KMT2AMEN1ALDH1A1PDE4AADORA2A | |
| SCHEMBL5436105 | 0.78 | ALDH1A1 (0.50) | KMT2AMEN1NSD2CASP6ALDH1A1 | |
| SCHEMBL5428518 | 0.78 | GAA (0.40) | KMT2AMEN1NSD2CASP6ALDH1A1 | |
| SCHEMBL13728723 | 0.77 | GAA (0.59) | KMT2AMEN1RAB9AALDH1A1TSHR | |
| SCHEMBL3141045 | 0.76 | KMT2A (0.43) | KMT2AMEN1RAB9AALDH1A1LMNA | |
| SCHEMBL15290224 | 0.75 | ALDH1A1 (0.56) | KMT2AMEN1GDACYP3A4PMP22 | |
| SCHEMBL7329915 | 0.73 | KDM4E (0.42) | KMT2AMEN1NSD2CASP6RAB9A | |
| SCHEMBL4090390 | 0.72 | CYP1A2 (0.46) | KMT2AMEN1CYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790252-B2 | 2-fluorinated riboses and arabinoses and methods of use and synthesis | CORNELL UNIVERSITY (US) | 2017-10-17 | — | — | US | disclosed |
| US-8481697-B2 | Nucleic acid base pairs | DAKO DENMARK A/S (DK) | 2013-07-09 | — | — | US | disclosed |
| US-20120108535-A1 | 2-FLUORINATED RIBOSES AND ARABINOSES AND METHODS OF USE AND SYNTHESIS | CORNELL UNIVERSITY (US) | 2012-05-03 | — | — | US | disclosed |
| US-20100105030-A1 | NUCLEIC ACID BASE PAIRS | DAKO DENMARK A/S (DK) | 2010-04-29 | — | — | US | disclosed |
| US-20070135454-A1 | Bicyclic pyrimidin-4(3h)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1-receptor(vr1) | BAYLISS TRACY | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135454-A1 | Bicyclic pyrimidin-4(3h)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1-receptor(vr1) | TRPV1, TRPV2, TRPV4 | KMT2A 4422/4885MEN1 4674/4885GDA 3791/4885 |
| US-20120108535-A1 | 2-FLUORINATED RIBOSES AND ARABINOSES AND METHODS OF USE AND SYNTHESIS | SLC2A2, SLC29A2, DERA | KMT2A 2015/4885MEN1 2120/4885GDA 307/4885 |
| US-20100105030-A1 | NUCLEIC ACID BASE PAIRS | NSUN3, NCL, NSUN2 | KMT2A 1811/4885MEN1 1256/4885GDA 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.