Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MGMT | P16455 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653894 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRHPGDLMNA | |
| SCHEMBL27634125 | 0.83 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRHPGDLMNA | |
| SCHEMBL6658253 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRHPGDBMP1 | |
| SCHEMBL6655757 | 0.80 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRHPGDLMNA | |
| SCHEMBL28536170 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRHPGDBMP1 | |
| SCHEMBL6653342 | 0.78 | TDP1 (0.50) | ALDH1A1TDP1TSHRHPGDLMNA | |
| SCHEMBL6297286 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRHPGDLMNA | |
| SCHEMBL647866 | 0.78 | TDP1 (0.56) | ALDH1A1TDP1TSHRMGMTMEN1 | |
| (Chloromethyl)Benzene SCHEMBL10786903 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRHPGDLMNA | |
| SCHEMBL11133058 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TDP1TSHRHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |