Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051094 | 0.88 | ALDH1A1 (0.58) | ALDH1A1POLBMEN1KMT2ACYP3A4 | |
| SCHEMBL11057721 | 0.84 | ALDH1A1 (0.41) | ALDH1A1POLBHTR2BDRD2HTR2A | |
| Hydrochloric Acid SCHEMBL11505527 | 0.84 | ALDH1A1 (0.41) | ALDH1A1POLBHTR2BDRD2HTR2A | |
| SCHEMBL10907867 | 0.83 | KMT2A (0.43) | ALDH1A1POLBHTR2BDRD2HTR2A | |
| SCHEMBL10905905 | 0.81 | ALDH1A1 (0.36) | ALDH1A1POLBHTR2BDRD2HTR2A | |
| Hydrochloric Acid SCHEMBL10905739 | 0.81 | KMT2A (0.42) | ALDH1A1POLBHTR2BDRD2HTR2A | |
| Lidamidine SCHEMBL122710 | 0.81 | POLB (0.58) | ALDH1A1POLBHTR2BDRD2HTR2A | |
| SCHEMBL10732186 | 0.81 | HTR2B (0.45) | ALDH1A1POLBHTR2BDRD2HTR2A | |
| SCHEMBL10906393 | 0.80 | ALDH1A1 (0.40) | ALDH1A1POLBHTR2BDRD2HTR2A | |
| SCHEMBL10905817 | 0.80 | HSD17B10 (0.38) | ALDH1A1POLBHTR2BDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |
| US-4562209-A | Promotion of feed efficiency in animals | WILLIAM H. RORER, INC. (US) | 1985-12-31 | — | — | US | disclosed |