Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13344922 | 0.76 | KDM4E (0.58) | AXLALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL12596867 | 0.74 | KDM4E (0.45) | PDE3BPDE3AAXLALDH1A1KDM4E | |
| SCHEMBL10908104 | 0.73 | CYP3A4 (0.37) | ALDH1A1HPGD | |
| SCHEMBL22408001 | 0.73 | GRIN2D (0.34) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11619589 | 0.70 | AXL (0.49) | MTNR1AMTNR1BAXLALDH1A1EHMT2 | |
| SCHEMBL34465699 | 0.70 | TNF (0.43) | MTNR1AMTNR1BMEN1KMT2APOLB | |
| SCHEMBL21884856 | 0.70 | AXL (0.49) | PDE3BPDE3AAXLALDH1A1LMNA | |
| SCHEMBL266817 | 0.68 | EHMT2 (0.62) | PDE3BPDE3AAXLALDH1A1KDM4E | |
| SCHEMBL476670 | 0.68 | ITK (0.48) | MTNR1AMTNR1BPDE3BPDE3AAXL | |
| SCHEMBL10908248 | 0.67 | MTNR1A (0.52) | MTNR1AMTNR1BPDE3BPDE3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614807-A | ANTIFERTILITY AGENTS | ELI LILLY AND COMPANY (US) | 1986-09-30 | — | — | US | disclosed |