Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | MPI | P34949 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10911207 | 0.98 | MAPT (0.57) | MAPTALDH1A1TP53HTTKDM4E | |
| SCHEMBL10845876 | 0.84 | MAPT (0.56) | MAPTALDH1A1TP53HTTKDM4E | |
| SCHEMBL10914542 | 0.79 | KDM4E (0.51) | MAPTALDH1A1TP53HTTKDM4E | |
| SCHEMBL29187832 | 0.79 | KDM4E (0.43) | MAPTALDH1A1TP53HTTKDM4E | |
| SCHEMBL30826406 | 0.79 | KDM4E (0.43) | MAPTALDH1A1TP53HTTKDM4E | |
| SCHEMBL10911937 | 0.78 | ALDH1A1 (0.42) | MAPTALDH1A1TP53HTTKDM4E | |
| SCHEMBL10767760 | 0.77 | KDM4E (0.50) | MAPTALDH1A1TP53HTTKDM4E | |
| SCHEMBL3950495 | 0.76 | ALDH1A1 (0.49) | MAPTALDH1A1TP53HTTKDM4E | |
| SCHEMBL10911484 | 0.74 | KDM4E (0.46) | MAPTALDH1A1TP53HTTKDM4E | |
| SCHEMBL10911930 | 0.74 | MEN1 (0.46) | MAPTALDH1A1TP53HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884684-A | Method for preparing 1,2,3,4-tetrahydroquinoline compound | 淮海工学院 | 2016-08-24 | — | — | CN | disclosed |
| EP-0103797-B1 | SUBSTITUTED BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 1986-11-26 | — | — | EP | disclosed |
| US-4537888-A | Substituted benzoxazine derivatives and fungicidal use | BAYER AKTIENGESELLSCHAFT (DE) | 1985-08-27 | — | — | US | disclosed |
| EP-0103797-A2 | Substituted benzoxazine derivatives | BAYER AG (DE) | 1984-03-28 | — | — | EP | disclosed |