Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1091564 | 0.99 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| SCHEMBL1091055 | 0.85 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| SCHEMBL742602 | 0.85 | SLC6A4 (0.82) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| SCHEMBL15304588 | 0.85 | SLC6A4 (0.82) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Hydrochloric Acid SCHEMBL743093 | 0.84 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Hydrochloric Acid SCHEMBL1545533 | 0.84 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| SCHEMBL221770 | 0.83 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Pudafensine SCHEMBL30747224 | 0.83 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Pudafensine SCHEMBL30747230 | 0.83 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Pudafensine SCHEMBL2316742 | 0.83 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989202-B1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2012-07-25 | — | — | EP | claimed |
| US-20100227883-A1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | ANIONA APS (DK) | 2010-09-09 | — | — | US | claimed |
| EP-1989202-A1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NeuroSearch A/S (DK) | 2008-11-12 | — | — | EP | claimed |
| WO-2007093604-A1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2007-08-23 | — | — | WO | claimed |
| EP-1989202-B1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2012-07-25 | — | — | EP | disclosed |
| US-8153797-B2 | Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2012-04-10 | — | — | US | disclosed |
| EP-2311835-A1 | Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NeuroSearch AS (DK) | 2011-04-20 | — | — | EP | disclosed |
| US-20100227883-A1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | ANIONA APS (DK) | 2010-09-09 | — | — | US | disclosed |
| EP-1989202-A1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NeuroSearch A/S (DK) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007093604-A1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227883-A1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC6A2, SLC18A2, SLC18A1 | SLC6A4 5/4885SLC6A2 1/4885SLC6A3 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.