Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.71 |
| ▸ | FPR2 | P25090 | 7/20 | 0.66 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.66 |
| ▸ | MME | P08473 | 1/20 | 0.61 |
| ▸ | ANPEP | P15144 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314395 | 1.00 | NAALAD2 (0.71) | NAALAD2FPR2FOLH1MMEANPEP | |
| SCHEMBL4316009 | 1.00 | NAALAD2 (0.71) | NAALAD2FPR2FOLH1MMEANPEP | |
| SCHEMBL18180178 | 0.94 | NAALAD2 (0.78) | NAALAD2FPR2FOLH1MMEL3MBTL1 | |
| SCHEMBL19969196 | 0.94 | NAALAD2 (0.78) | NAALAD2FPR2FOLH1MMEL3MBTL1 | |
| SCHEMBL27545036 | 0.86 | NAALAD2 (0.73) | NAALAD2FPR2FOLH1MMEALDH1A1 | |
| SCHEMBL11687358 | 0.84 | NAALAD2 (0.61) | NAALAD2FPR2ANPEPALDH1A1KMT2A | |
| SCHEMBL11936654 | 0.83 | NAALAD2 (1.00) | NAALAD2FOLH1 | |
| SCHEMBL13700588 | 0.83 | FOLH1 (0.78) | NAALAD2FOLH1MMEALDH1A1MEN1 | |
| SCHEMBL11936623 | 0.83 | NAALAD2 (1.00) | NAALAD2FOLH1 | |
| SCHEMBL547222 | 0.83 | MME (0.67) | NAALAD2FPR2FOLH1MMEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618692-A | ANTITUMOR AGENTS | ASTA-WERKE AKTIENGESELLSCHAFT (DE) | 1986-10-21 | — | — | US | disclosed |