SCHEMBL547222

SCHEMBL547222

O=C(O)N[C@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MME P08473 4/20 0.67
L3MBTL1 Q9Y468 1/20 0.66
NPSR1 Q6W5P4 1/20 0.65
NAALAD2 Q9Y3Q0 2/20 0.63
ACE2 Q9BYF1 3/20 0.59
ACE P12821 2/20 0.59
CPA1 P15085 2/20 0.59
FPR2 P25090 5/20 0.58
PTPN1 P18031 1/20 0.58
FOLH1 Q04609 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547223 1.00 MME (0.67) MMEL3MBTL1NPSR1NAALAD2ACE2
SCHEMBL1696507 1.00 MME (0.67) MMEL3MBTL1NPSR1NAALAD2ACE2
SCHEMBL18180178 0.88 NAALAD2 (0.78) MMEL3MBTL1NPSR1NAALAD2FPR2
SCHEMBL19969196 0.88 NAALAD2 (0.78) MMEL3MBTL1NPSR1NAALAD2FPR2
SCHEMBL10795720 0.87 MME (0.62) MMEL3MBTL1NPSR1NAALAD2ACE2
SCHEMBL5841327 0.86 MME (0.65) MMEL3MBTL1NPSR1NAALAD2ACE2
SCHEMBL1012053 0.85 MME (0.63) MMEL3MBTL1NPSR1NAALAD2ACE2
Afalanine SCHEMBL331330 0.85 CTSS (0.65) MMEL3MBTL1NPSR1NAALAD2ACE2
SCHEMBL4028404 0.85 ALDH1A1 (0.57) MMEL3MBTL1
SCHEMBL17785192 0.85 MME (0.68) MMEL3MBTL1NPSR1NAALAD2ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2508611-B1 Process for production of triprenyl phenol compounds TMS CO LTD (JP) 2019-05-08 EP claimed
EP-2508611-B1 Process for production of triprenyl phenol compounds TMS CO LTD (JP) 2019-05-08 EP disclosed
EP-2604697-B1 Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) 2015-07-01 EP disclosed
US-8883462-B2 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2014-11-11 US disclosed
EP-2000540-B1 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) 2014-05-14 EP disclosed
EP-2604697-A1 Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer Tokyo University of Agriculture and Technology TLO (JP) 2013-06-19 EP disclosed
EP-2508611-A1 Process for production of triprenyl phenol compounds Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) 2012-10-10 EP disclosed
US-20120100579-A1 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER TOKYO UNIVERSITY OF AGRICLATURE AND TECHNOLOGY TLO CO., LTD. (JP) 2012-04-26 US disclosed
US-8110596-B2 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2012-02-07 US disclosed
US-20090216028-A1 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2009-08-27 US disclosed
EP-2000540-A9 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) 2009-03-25 EP disclosed
EP-2000540-A2 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER Tokyo University of Agriculture and Technology TLO Co., Ltd. (JP) 2008-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090216028-A1 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer PLAT, F2R, F12 MME 43/4885L3MBTL1 3731/4885NPSR1 103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.