Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024487 | 0.87 | BACE1 (0.62) | HTTHPGDALDH1A1PTPN1BACE1 | |
| SCHEMBL16742152 | 0.85 | HTT (0.68) | HTTHPGDALDH1A1PTPN1CA1 | |
| SCHEMBL15660164 | 0.84 | CA1 (0.59) | HTTHPGDALDH1A1PTPN1CA1 | |
| 3-Prenyl-4-Hydroxyacetophenone SCHEMBL4120403 | 0.84 | HTT (1.00) | HTTHPGDALDH1A1PTPN1XDH | |
| SCHEMBL20660848 | 0.84 | HTT (0.50) | HTTHPGDALDH1A1PTPN1CA1 | |
| SCHEMBL542210 | 0.83 | CA1 (0.57) | HTTHPGDALDH1A1PTPN1CA1 | |
| SCHEMBL30392187 | 0.83 | HTT (0.79) | HTTHPGDALDH1A1PTPN1CA1 | |
| SCHEMBL1607531 | 0.83 | HTT (0.79) | HTTHPGDALDH1A1PTPN1CA1 | |
| SCHEMBL19061607 | 0.82 | HTT (0.72) | HTTHPGDALDH1A1PTPN1XDH | |
| SCHEMBL8451865 | 0.82 | CA1 (0.56) | HTTHPGDALDH1A1PTPN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4594460-A | Process for selective C-alkylation of phenols | RHONE-POULENC SANTE (FR) | 1986-06-10 | — | — | US | disclosed |