Sugi Predict

Sugi Predict / Compounds / SCHEMBL542210

SCHEMBL542210

SCHEMBL542210

C=CCc1cc(C(=O)OC)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 3/20 0.57
▸ CA2 P00918 3/20 0.57
▸ CA12 O43570 2/20 0.57
▸ CA7 P43166 2/20 0.57
▸ CA9 Q16790 2/20 0.57
▸ CA14 Q9ULX7 2/20 0.57
▸ XDH P47989 1/20 0.57
▸ ALDH1A1 P00352 4/20 0.55
▸ HPGD P15428 4/20 0.55
▸ HTT P42858 4/20 0.55
▸ LMNA P02545 2/20 0.55
▸ GABRA1 P14867 1/20 0.53
▸ GABRB2 P47870 1/20 0.53
▸ PTPN1 P18031 5/20 0.52
▸ TP53 P04637 2/20 0.51
▸ ALOX15 P16050 2/20 0.51
▸ ALOX12 P18054 2/20 0.51
▸ HSD17B10 Q99714 2/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ MEN1 O00255 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL502441 0.88 ALDH1A1 (0.48) CA1CA2CA12CA7CA9
SCHEMBL6478663 0.88 XDH (0.57) CA1CA2CA12CA7CA9
SCHEMBL15660164 0.86 CA1 (0.59) CA1CA2CA12CA7CA9
SCHEMBL1515872 0.85 CA12 (0.62) CA1CA2CA12CA7CA9
SCHEMBL5586280 0.84 KDM4E (0.53) CA1CA2CA12CA7CA9
SCHEMBL8419839 0.84 HDAC6 (0.50) CA1CA2CA12CA7CA9
SCHEMBL8772573 0.84 CA12 (0.60) CA1CA2CA12CA7CA9
SCHEMBL8772579 0.84 HTT (0.51) CA1CA2CA12CA9CA14
SCHEMBL23027982 0.83 NOTUM (0.50) CA1CA2CA12CA7CA9
SCHEMBL3542900 0.83 PTPN1 (0.57) GABRA1GABRB2PTPN1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61027281-A — — None — — JP disclosed
US-12486258-B2 Compounds and methods for regulating insulin secretion THE BROAD INSTITUTE, INC. (US) 2025-12-02 — — US disclosed
US-12458624-B2 Deuterium-enriched substituted phenoxyphenyl acetic acids and acylsulfonamides DHANOA DALJIT SINGH (US) 2025-11-04 — — US disclosed
US-20230142508-A1 COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION THE BROAD INSTITUTE, INC. (US) 2023-05-11 — — US disclosed
US-20230142508-A1 COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION THE BROAD INSTITUTE, INC. (US) 2023-05-11 — — US disclosed
US-20230142508-A1 COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION THE BROAD INSTITUTE, INC. (US) 2023-05-11 — — US disclosed
US-20230039319-A1 DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES DHANOA DALJIT SINGH (US) 2023-02-09 — — US disclosed
US-11555031-B2 Compounds and methods for regulating insulin secretion THE BROAD INSTITUTE, INC. (US) 2023-01-17 — — US disclosed
WO-2021118826-A1 DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES DHANOA DALJIT (US) 2021-06-17 — — WO disclosed
US-10953012-B2 Heterocyclic compounds for the inhibition of pask BIOENERGENIX LLC (US) 2021-03-23 — — US disclosed
WO-1991012001-A1 ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT MERCK & CO., INC. (US) 1991-08-22 — — WO disclosed
WO-1991011999-A1 ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT MERCK & CO., INC. (US) 1991-08-22 — — WO disclosed
WO-1991011909-A1 TRIAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT MERCK & CO., INC. (US) 1991-08-22 — — WO disclosed
EP-0193853-B1 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-09-12 — — EP disclosed
EP-0150447-B1 SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLATES G.D. Searle & Co. (US) 1990-01-24 — — EP disclosed
US-4783462-A 3(2H)pyridazinone, and anti-allergic agent containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1988-11-08 — — US disclosed
EP-0193853-A2 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1986-09-10 — — EP disclosed
JP-S6127281-A RECORDING MATERIAL FUJI PHOTO FILM CO LTD 1986-02-06 — — JP disclosed
US-4565882-A Substituted dihydrobenzopyran-2-carboxylates G. D. SEARLE & CO. (US) 1986-01-21 — — US disclosed
EP-0150447-A2 Substituted dihydrobenzopyran-2-carboxylates G.D. Searle & Co. (US) 1985-08-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230039319-A1 DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES AGTR2, AGTR1, EDNRA CA1 2870/4885CA2 574/4885CA12 2967/4885
US-20230142508-A1 COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION IAPP, GPR119, PNLIP CA1 2634/4885CA2 2276/4885CA12 3325/4885
US-11555031-B2 Compounds and methods for regulating insulin secretion IAPP, GPR119, INSR CA1 2703/4885CA2 2366/4885CA12 3073/4885
US-12486258-B2 Compounds and methods for regulating insulin secretion IAPP, GPR119, PNLIP CA1 2634/4885CA2 2276/4885CA12 3325/4885
US-12458624-B2 Deuterium-enriched substituted phenoxyphenyl acetic acids and acylsulfonamides AGTR2, AGTR1, EDNRA CA1 2870/4885CA2 574/4885CA12 2967/4885
US-10953012-B2 Heterocyclic compounds for the inhibition of pask PASK, PDXK, PANK2 CA1 4318/4885CA2 3112/4885CA12 4760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.