Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.55 |
| ▸ | HTR2A | P28223 | 4/20 | 0.55 |
| ▸ | HRH1 | P35367 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.55 |
| ▸ | HRH2 | P25021 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908777 | 0.96 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL10913445 | 0.93 | SIGMAR1 (0.53) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL10911293 | 0.92 | SIGMAR1 (0.55) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL10910544 | 0.91 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL10908769 | 0.89 | SIGMAR1 (0.55) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL10911161 | 0.87 | SIGMAR1 (0.58) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL10911263 | 0.87 | SIGMAR1 (0.58) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL10911095 | 0.86 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3LMNACHRM2 | |
| SCHEMBL10911244 | 0.85 | HRH1 (0.50) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL10911318 | 0.85 | SIGMAR1 (0.48) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4620036-A | Diphenylalkanoether and diphenylalkanone oximeether derivatives | ONO KEIICHI (JP) | 1986-10-28 | — | — | US | disclosed |
| EP-0017217-B1 | DIPHENYLALKANOETHER AND DIPHENYLALKANONE OXIMEETHER DERIVATIVES, A PROCESS FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-03-13 | — | — | EP | disclosed |
| US-4482573-A | Diphenylalkanoether and diphenylalkanone oximeether derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-13 | — | — | US | disclosed |
| US-4459410-A | Diphenylalkanoether derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-07-10 | — | — | US | disclosed |
| US-4426394-A | Diphenylalkanoether and diphenylalkanone oximeether derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1984-01-17 | — | — | US | disclosed |
| US-4388469-A | Diphenylalkanoether and diphenylalkanone oximeether derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-14 | — | — | US | disclosed |
| EP-0017217-A2 | Diphenylalkanoether and diphenylalkanone oximeether derivatives, a process for their production, pharmaceutical compositions and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-10-15 | — | — | EP | disclosed |