Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115 | 0.90 | FOLH1 (0.61) | KDM4EFOLH1CLCN2ALDH1A1ALOX15 | |
| SCHEMBL6912613 | 0.88 | FOLH1 (0.59) | KDM4EFOLH1CLCN2ALDH1A1ALOX15 | |
| Ammonia Solution, Strong SCHEMBL22042013 | 0.88 | FOLH1 (0.59) | KDM4EFOLH1CLCN2ALDH1A1ALOX15 | |
| SCHEMBL6915613 | 0.88 | FOLH1 (0.59) | KDM4EFOLH1CLCN2ALDH1A1ALOX15 | |
| SCHEMBL6914507 | 0.88 | FOLH1 (0.59) | KDM4EFOLH1CLCN2ALDH1A1ALOX15 | |
| SCHEMBL6916475 | 0.88 | FOLH1 (0.59) | KDM4EFOLH1CLCN2ALDH1A1ALOX15 | |
| SCHEMBL6912943 | 0.88 | FOLH1 (0.59) | KDM4EFOLH1CLCN2ALDH1A1ALOX15 | |
| SCHEMBL6914874 | 0.88 | FOLH1 (0.59) | KDM4EFOLH1CLCN2ALDH1A1ALOX15 | |
| Phthalic Acid SCHEMBL45284 | 0.88 | ALDH1A1 (0.64) | KDM4EPOLBALDH1A1ALOX15TSHR | |
| Bromide SCHEMBL3173857 | 0.88 | FOLH1 (0.59) | KDM4EFOLH1CLCN2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563512-A | AROMATIC ESTER AND ALIPHATIC ETHER OR TERTIARY AMINE | SHELL OIL COMPANY (US) | 1986-01-07 | — | — | US | disclosed |