SCHEMBL10909232

SCHEMBL10909232

Clc1ccc(-c2ccc(-c3ccc(Cl)cc3)o2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
NPSR1 Q6W5P4 1/20 0.57
NOTUM Q6P988 4/20 0.50
MAPT P10636 2/20 0.50
PKM P14618 2/20 0.50
HPGD P15428 2/20 0.50
HTT P42858 2/20 0.50
KDM4E B2RXH2 1/20 0.50
GFER P55789 1/20 0.50
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
SLC9A1 P19634 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CYP2A6 P11509 1/20 0.47
ERCC5 P28715 1/20 0.47
FEN1 P39748 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10613612 0.90 CYP1A2 (0.64) ALDH1A1NPSR1MAPTPKMHPGD
SCHEMBL10953805 0.88 ALDH1A1 (0.48) ALDH1A1NPSR1MAPTPKMHPGD
SCHEMBL2615713 0.83 ALDH1A1 (0.48) ALDH1A1NPSR1NOTUMMAPTPKM
SCHEMBL5536007 0.83 ALDH1A1 (0.48) ALDH1A1NPSR1NOTUMMAPTPKM
SCHEMBL8926649 0.83 ALDH1A1 (0.48) ALDH1A1NPSR1NOTUMMAPTPKM
SCHEMBL11621135 0.79 ALDH1A1 (0.65) ALDH1A1NPSR1NOTUMMAPTPKM
SCHEMBL17165560 0.78 CYP1A2 (0.54) ALDH1A1NPSR1MAPTPKMHPGD
SCHEMBL11505498 0.78 CYP3A4 (0.66) ALDH1A1NPSR1NOTUMMAPTPKM
SCHEMBL10555140 0.78 ALDH1A1 (0.44) ALDH1A1NPSR1NOTUMMAPTPKM
SCHEMBL2322085 0.78 ALDH1A1 (0.44) ALDH1A1NPSR1NOTUMMAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4563413-A PHOTORESISTS, PRINTING PLATES HERCULES INCORPORATED (US) 1986-01-07 US disclosed