Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31159190 | 0.89 | MEN1 (0.41) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3713818 | 0.81 | MEN1 (0.49) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2361634 | 0.81 | PARP1 (0.33) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10912290 | 0.78 | MEN1 (0.39) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10909711 | 0.78 | KDM4E (0.42) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4941638 | 0.78 | MEN1 (0.39) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2333372 | 0.78 | KDM4E (0.34) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10912376 | 0.77 | AR (0.40) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30841789 | 0.76 | PARP1 (0.33) | PARP1 | |
| SCHEMBL10909321 | 0.74 | ALDH1A1 (0.42) | KDM4EMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173208-A1 | Tetrahydroquinolin-1-yl-carbonyl-imidazole derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-03-05 | — | — | EP | disclosed |