Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 9/20 | 0.36 |
| ▸ | HTR2A | P28223 | 7/20 | 0.36 |
| ▸ | HTR2B | P41595 | 7/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10947809 | 0.82 | DDB1 (0.46) | DDB1CRBNHTR2CHTR2AHTR2B | |
| SCHEMBL11215533 | 0.79 | DDB1 (0.46) | DDB1CRBNHTR2CHTR2AHTR2B | |
| SCHEMBL11215343 | 0.72 | DDB1 (0.40) | DDB1CRBNHTR2CHTR2AHTR2B | |
| SCHEMBL11226212 | 0.71 | TSHR (0.41) | HTR2CHTR2AHTR2BALDH1A1NOS2 | |
| SCHEMBL11215167 | 0.68 | DDB1 (0.47) | DDB1CRBNHTR2CHTR2AHTR2B | |
| SCHEMBL1643784 | 0.67 | KDM1A (0.47) | HTR2CHTR2AHTR2BSLC6A9SLC6A5 | |
| SCHEMBL1643782 | 0.67 | KDM1A (0.47) | HTR2CHTR2AHTR2BSLC6A9SLC6A5 | |
| SCHEMBL1643791 | 0.67 | KDM1A (0.47) | HTR2CHTR2AHTR2BSLC6A9SLC6A5 | |
| SCHEMBL8125269 | 0.67 | HTR2C (0.46) | DDB1CRBNHTR2CHTR2AHTR2B | |
| Biphenyl SCHEMBL9937258 | 0.65 | HTR2C (0.58) | DDB1CRBNHTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613617-A | Synergistic insecticidal compositions containing dione esters | UNION CARBIDE CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0007243-B1 | 2-ARYL-1,3-CYCLOHEXANEDIONE COMPOUNDS AND ALKALI METAL SALTS, AMMONIUM SALTS AND ENOL ESTERS THEREOF, COMPOSITION AND METHOD OF CONTROLLING ACARINA ECTOPARASITES ON WARMBLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4257858-A | REACTING A CYCLOHEXA-1,3-DIONE-2-DIAZIDE WITH AN ARYL COMPOUND | UNION CARBIDE CORPORATION (US) | 1981-03-24 | — | — | US | disclosed |
| US-4256657-A | CYCLIZATION, ACID CATALYST | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4256658-A | CYCLIZATION, BASIC CATALYST | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4256659-A | Method of preparing 2-aryl-1,3-cyclohexanedione compounds | UNION CARBIDE CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |
| US-4209532-A | Biocidal 2-aryl-1,3-cyclohexane dione compounds and alkali metal and ammonium salts thereof | UNION CARBIDE CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| EP-0007243-A1 | 2-Aryl-1,3-cyclohexanedione compounds and alkali metal salts, ammonium salts and enol esters thereof, composition and method of controlling acarina ectoparasites on warmblooded animals | UNION CARBIDE CORPORATION (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4175135-A | Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof | UNION CARBIDE CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |