Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892722 | 0.86 | KDM4E (0.58) | SMPD1HDAC1HDAC8HDAC6NPC1 | |
| SCHEMBL10436239 | 0.86 | KMT2A (0.60) | NPC1HPGDRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11007596 | 0.85 | SMPD1 (0.57) | SMPD1HDAC1HDAC8HDAC6MRGPRX4 | |
| SCHEMBL7713567 | 0.85 | FFAR4 (0.56) | MRGPRX4RXRAHIF1AMEN1KMT2A | |
| SCHEMBL8683738 | 0.85 | PDE4A (0.63) | MRGPRX4L3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL10799614 | 0.84 | NPC1 (0.57) | SMPD1HDAC1HDAC8HDAC6MRGPRX4 | |
| SCHEMBL27598175 | 0.83 | KMT2A (0.50) | HIF1AMEN1KMT2ATDP1MAPT | |
| SCHEMBL14451128 | 0.83 | FFAR1 (0.54) | SMPD1HDAC1HDAC8HDAC6MRGPRX4 | |
| SCHEMBL11011195 | 0.82 | SMPD1 (0.54) | SMPD1HDAC1HDAC8HDAC6MRGPRX4 | |
| SCHEMBL8844454 | 0.82 | SLC6A2 (0.60) | SMPD1HDAC1HDAC8HDAC6MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579748-A | Foodstuff containing 3-hydroxy-4-methoxyphenyl benzoates | GENERAL FOODS CORP. (US) | 1986-04-01 | — | — | US | disclosed |
| US-4547584-A | 3-Hydroxy-4-methoxyphenyl benzoates | GENERAL FOODS CORPORATION (US) | 1985-10-15 | — | — | US | disclosed |
| EP-0151293-A2 | 3-hydroxy-4-methoxyphenyl benzoates, process for modifying the sweetness perception in a foodstuff and foodstuff compositions containing said sweetening agents | GENERAL FOODS CORPORATION (US) | 1985-08-14 | — | — | EP | disclosed |