Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766113 | 1.00 | ESR2 (0.52) | ESR2GRIA1GRIA2GRIA3HRH3 | |
| SCHEMBL14649679 | 0.95 | HRH3 (0.50) | ESR2GRIA1GRIA2GRIA3HRH3 | |
| SCHEMBL16488063 | 0.94 | ESR2 (0.57) | ESR2GRIA1GRIA2GRIA3HRH3 | |
| SCHEMBL30150 | 0.94 | ESR2 (0.57) | ESR2GRIA1GRIA2GRIA3HRH3 | |
| SCHEMBL20083485 | 0.94 | ESR2 (0.57) | ESR2GRIA1GRIA2GRIA3HRH3 | |
| SCHEMBL13621591 | 0.91 | GRIA1 (0.46) | ESR2GRIA1GRIA2GRIA3HRH3 | |
| SCHEMBL11524397 | 0.89 | HRH3 (0.54) | ESR2GRIA1GRIA2GRIA3HRH3 | |
| SCHEMBL14649680 | 0.89 | HRH3 (0.54) | ESR2GRIA1GRIA2GRIA3HRH3 | |
| SCHEMBL11524401 | 0.89 | HRH3 (0.54) | ESR2GRIA1GRIA2GRIA3HRH3 | |
| SCHEMBL13100711 | 0.88 | HRH3 (0.46) | ESR2GRIA1GRIA2GRIA3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4620938-A | Hydroterphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-11-04 | — | — | US | disclosed |